Editando Esteban (sección)

==Investigation and findings==
The scientific work of Dr. Picado was prolific and very extensive; it is calculated that he wrote about 115 research papers in his lifetime, delving into nearly all aspects of his environment: soil, flora, fauna, human tissues, water, and others.<ref name="CP">{{cite news | title=Dr. Clodomiro Picado Twight Honored with WIPO medal | url =http://www.wipo.int/wipo_magazine/en/pdf/2000/wipo_pub_121_2000_07-08.pdf | work =WIPO Magazine | pages =11 | accessdate = 2008-03-02|format=PDF}}</ref> Among them are included books and monographs. His work covered topics of zoology, botany of [[bromeliad]]s, [[ophidism]], physiology, [[phytopathology]], [[industrial microbiology]], medical microbiology, and immunology.

In March 2000, doctors from the San Juan de Dios Hospital in [[San José, Costa Rica|San José]], the capital of Costa Rica, published his manuscripts, in which he explains his experiences between 1915 and 1927 with the inhibiting action of fungi of the ''[[Penicillium]]'' [[genus]] in the growth of ''[[Staphylococcus|Staphylococci]]'' and ''[[Streptococcus|Streptococci]]'' (bacteria that cause a series of infections). In 1927, he demonstrated the inhibitory action of the fungal genus ''Penicillium'' on the proliferation of the bacteria ''Staphylococcus'' and ''Streptococcus''. Although, the discovery of penicillin has been attributed to [[Alexander Fleming]], Picado's old laboratory notebooks from 1923 show records of the antibiosis of ''Penicillium'' sp.<ref name="CP"/>

For this reason he is renowned as one of the precursors of the penicillin antibiotic. The report with the results of the treatments performed with penicillin by Dr. Picado were published by the Biology Society of Paris in 1927.<ref>{{cite news | first=Enrique | last=Tovar | title=El legado de Clorito | url=http://www.nacion.com/ln_ee/ESPECIALES/tiempo2000/figuras2.html | work=Nacion | accessdate=2008-03-02 | language=Spanish | archive-url=https://web.archive.org/web/20090404043307/http://www.nacion.com/ln_ee/ESPECIALES/tiempo2000/figuras2.html | archive-date=2009-04-04 | url-status=dead }}</ref>